Cyclohexene → HCID 135449092, compound

HRID 1294955Notes

Reaction equation

HRID 1294955 reaction equation
[F:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][CH:15]=3)[N:8]([CH:11]([CH3:13])[CH3:12])[N:9]=2)[C:5](C)=[CH:4][CH:3]=1.B(Br)(Br)Br.C1CCCCC=1>>[F:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:15]=[CH:16][C:17]([OH:20])=[CH:18][CH:19]=3)[N:8]([CH:11]([CH3:12])[CH3:13])[N:9]=2)[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68884869HCID 68884869, compound

Product 1

HCID 135449092HCID 135449092, compoundYield 88.8%

Procedure

Prepared according to Method D step C from 7-fluoro-2-isopropyl-3-(4-methoxyphenyl)-methyl-2H-indazole (0.007 g, 0.025 mmol), boron tribromide (0.05 mL, 0.5 mmol) and 0.2 mL of cyclohexene to give the product (0.006 g).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e8fe97682d6b4ab7809c6ba63f3ef60e
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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