Cyclohexene → HCID 136358444, compound

HRID 1294959Notes

Reaction equation

HRID 1294959 reaction equation
[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[C:13]([F:16])([F:15])[F:14])[C:6]([C:17]2[CH:22]=[CH:21][C:20]([O:23]C)=[CH:19][CH:18]=2)=[N:5]1)[CH:2]=[CH2:3].B(Br)(Br)Br.C1CCCCC=1>>[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[C:13]([F:16])([F:15])[F:14])[C:6]([C:17]2[CH:18]=[CH:19][C:20]([OH:23])=[CH:21][CH:22]=2)=[N:5]1)[CH:2]=[CH2:3]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68884329HCID 68884329, compound

Product 1

HCID 136358444HCID 136358444, compoundYield 94.3%

Procedure

Prepared according to Method D step C from 1-allyl-3-(4-methoxyphenyl)-7-trifluoromethyl-1H-indazole (0.027 g, 0.08 mmol), boron tribromide (0.10 mL, 1.05 mmol) and 0.3 mL of cyclohexene to give the product (0.024 g) as a grey solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-66db2bd5b140428dbccb4af230644701
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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