HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexene → 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)-2-methylphenol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexene | HCID 8079 | — |
| Reactant | Boron tribromide | HCID 25134 | — |
| Reactant | 1-cyclopentyl-7-fluoro-3-(4-methoxy-3-methylphenyl)-1H-indazole | HCID 68884760 | — |
| Product | 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)-2-methylphenol | HCID 136358445 | 22.4% |
Reaction Steps
Prepared according to Method D step C from 1-cyclopentyl-7-fluoro-3-(4-methoxy-3-methylphenyl)-1H-indazole (0.70 g, 2.16 mmol), boron tribromide (0.82 mL, 8.6 mmol) and 1.0 mL of cyclohexene to give the product (0.15 g) as a white solid, mp 107° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-9f65e4f6dd3541d789091a8825a79251 |
| Source note | uspto-grants-2007_07 |