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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1294986Generated: October 30, 2026

Cyclohexene → 3-methyl-4-[1-propyl-7-(trifluoromethyl)-1H-indazol-3-yl]phenol

https://huagongshe.com/reaction/1294986

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclohexeneHCID 8079—
ReactantBoron tribromideHCID 25134—
Reactant3-(4-methoxy-2-methylphenyl)-1-propyl-7-(trifluoromethyl)-1H-indazoleHCID 68884613—
Product3-methyl-4-[1-propyl-7-(trifluoromethyl)-1H-indazol-3-yl]phenolHCID 136358452108.9%

Reaction Steps

Prepared according to Method D step C from 3-(4-methoxy-2-methylphenyl)-1-propyl-7-(trifluoromethyl)-1H-indazole (0.087 g, 0.25 mmol), boron tribromide (0.136 mL, 1.4 mmol) and 1.0 mL of cyclohexene to give the product (0.091 g) as a white solid,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241791B2
Source datasetuspto-grants-2007_07
ORD IDord-4e32b2f6db434fe7b2c31787dfce80ab
Source noteuspto-grants-2007_07