Cyclohexene → HCID 136358453, compound

HRID 1294988Notes

Reaction equation

HRID 1294988 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:13])[CH3:12])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=1[CH3:22].B(Br)(Br)Br.C1CCCCC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:13])[CH3:12])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=1[CH3:22]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68883258HCID 68883258, compound

Product 1

HCID 136358453HCID 136358453, compoundYield 53.2%

Procedure

Prepared according to Method D step C from 7-chloro-1-isopropyl-3-(4-methoxy-2-methylphenyl)-1H-indazole (0.090 g, 0.3 mmol), boron tribromide (0.104 mL, 1.1 mmol) and 1.0 mL of cyclohexene to give the product (0.048 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-9ae77c87418940f7859a2cebaaf5e6e1
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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