Cyclohexene → HCID 136358454, compound

HRID 1294992Notes

Reaction equation

HRID 1294992 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:13])[CH3:12])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=1[O:22]C.B(Br)(Br)Br.C1CCCCC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:13])[CH3:12])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=1[OH:22]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68883580HCID 68883580, compound

Product 1

HCID 136358454HCID 136358454, compoundYield 74.3%

Procedure

Prepared according to Method D step C from 7-chloro-3-(2,4-dimethoxyphenyl)-1-isopropyl-1H-indazole (0.132 g, 0.4 mmol), boron tribromide (0.377 mL, 4.0 mmol) and 1.0 mL of cyclohexene to give the product (0.090 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d8124537460e4b4caed4f55d2f4f0699
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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