Cyclohexene → HCID 136358456, compound

HRID 1294996Notes

Reaction equation

HRID 1294996 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]1CC[CH2:13][CH2:12]1)[N:8]=[C:7]2[C:16]1[CH:21]=[CH:20][C:19]([O:22]C)=[CH:18][C:17]=1[CH3:24].B(Br)(Br)Br.C1CCCCC=1>>[CH2:11]([N:9]1[C:10]2[C:6](=[CH:5][CH:4]=[CH:3][C:2]=2[Cl:1])[C:7]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][C:17]=2[CH3:24])=[N:8]1)[CH:12]=[CH2:13]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68885366HCID 68885366, compound

Product 1

HCID 136358456HCID 136358456, compoundYield 100.4%

Procedure

Prepared according to Method D step C from 7-chloro-1-cyclopentyl-3-(4-methoxy-2-methylphenyl)-1H-indazole (0.102 g, 0.33 mmol), boron tribromide (0.19 mL, 2.0 mmol) and 1.0 mL of cyclohexene to give the product (0.099 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e7b05dac920244568b3f6e1d3181a95c
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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