Cyclohexene → HCID 135507439, compound

HRID 1294998Notes

Reaction equation

HRID 1294998 reaction equation
[CH:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[C:13]([F:16])([F:15])[F:14])[C:6]([C:17]2[CH:22]=[CH:21][C:20]([O:23]C)=[CH:19][C:18]=2[CH3:25])=[N:5]1)([CH3:3])[CH3:2].B(Br)(Br)Br.C1CCCCC=1>>[CH:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[C:13]([F:16])([F:15])[F:14])[C:6]([C:17]2[CH:22]=[CH:21][C:20]([OH:23])=[CH:19][C:18]=2[CH3:25])=[N:5]1)([CH3:3])[CH3:2]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68882666HCID 68882666, compound

Product 1

HCID 135507439HCID 135507439, compoundYield 139.1%

Procedure

Prepared according to Method D step C from 1-isopropyl-3-(4-methoxy-2-methylphenyl)-7-(trifluoromethyl)-1H-indazole (0.062 g, 0.2 mmol), boron tribromide (0.067 mL, 0.7 mmol) and 1.0 mL of cyclohexene to give the product (0.093 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4c1800194dd3421d940d89392262bc91
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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