Cyclohexene → HCID 136358457, compound

HRID 1295000Notes

Reaction equation

HRID 1295000 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1)[N:8]=[C:7]2[C:16]1[CH:21]=[CH:20][C:19]([O:22]C)=[CH:18][C:17]=1[CH3:24].B(Br)(Br)Br.C1CCCCC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]1[CH2:15][CH2:14][CH2:13][CH2:12]1)[N:8]=[C:7]2[C:16]1[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][C:17]=1[CH3:24]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68885366HCID 68885366, compound

Product 1

HCID 136358457HCID 136358457, compoundYield 41.2%

Procedure

Prepared according to Method D step C from 7-chloro-1-cyclopentyl-3-(4-methoxy-2-methylphenyl)-1H-indazole (0.090 g, 0.26 mmol), boron tribromide (0.100 mL, 1.0 mmol) and 1.0 mL of cyclohexene to give the product (0.035 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-28eb2d6fb26e4b8fa95ecc600cb9b420
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

Loading…