Cyclohexene → HCID 136358459, compound

HRID 1295003Notes

Reaction equation

HRID 1295003 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][CH3:13])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=1[CH3:22].B(Br)(Br)Br.C1CCCCC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][CH3:13])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=1[CH3:22]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68885270HCID 68885270, compound

Product 1

HCID 136358459HCID 136358459, compoundYield 80.9%

Procedure

Prepared according to Method D step C from 7-chloro-3-(4-methoxy-2-methylphenyl)-1-propyl-1H-indazole (0.90 g, 0.3 mmol), boron tribromide (0.113 mL, 1.20 mmol) and 1.0 mL of cyclohexene to give the product (0.073 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-855d455f947a409bb5757e43d5dd1c7f
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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