Cyclohexene → HCID 136358463, compound

HRID 1295010Notes

Reaction equation

HRID 1295010 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:13])[CH3:12])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=1[CH3:22].B(Br)(Br)Br.C1CCCCC=1>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH:11]([CH3:13])[CH3:12])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=1[CH3:22]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68883614HCID 68883614, compound

Product 1

HCID 136358463HCID 136358463, compoundYield 101.3%

Procedure

Prepared according to Method D step C from 7-fluoro-1-isopropyl-3-(4-methoxy-2-methylphenyl)-1H-indazole (0.151 g, 0.500 mmol), boron tribromide (0.118 mL, 1.25 mmol) and 1.0 mL of cyclohexene to give the product (0.144 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-502a3ecf091b4fe78eb2ee30be559320
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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