Cyclohexene → HCID 136358464, compound

HRID 1295012Notes

Reaction equation

HRID 1295012 reaction equation
[F:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=3[CH3:22])[N:8]([CH2:11][CH2:12][CH3:13])[N:9]=2)[CH:5]=[CH:4][CH:3]=1.B(Br)(Br)Br.C1CCCCC=1>>[F:1][C:2]1[C:10]2[C:6](=[C:7]([C:14]3[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=3[CH3:22])[N:8]([CH2:11][CH2:12][CH3:13])[N:9]=2)[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68885969HCID 68885969, compound

Product 1

HCID 136358464HCID 136358464, compoundYield 91.4%

Procedure

Prepared according to Method D step C from 7-fluoro-3-(4-methoxy-2-methylphenyl)-2-propyl-2H-indazole (0.059 g, 0.20 mmol), boron tribromide (0.05 mL, 0.5 mmol) and 1.0 mL of cyclohexene to give the product (0.052 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-2fa38221b6e1401793f9e9ec202ec0a2
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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