Cyclohexene → HCID 136358465, compound

HRID 1295014Notes

Reaction equation

HRID 1295014 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][CH3:13])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=1[CH3:22].B(Br)(Br)Br.C1CCCCC=1>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][CH3:13])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=1[CH3:22]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68883823HCID 68883823, compound

Product 1

HCID 136358465HCID 136358465, compoundYield 98.5%

Procedure

Prepared according to Method D step C from 7-fluoro-3-(4-methoxy-2-methylphenyl)-1-propyl-1H-indazole (0.268 g, 0.90 mmol), boron tribromide (0.275 mL, 2.90 mmol) and 1.0 mL of cyclohexene to give the product (0.252 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-38a2ca54ef7f4b8d81c4fb8a54ae73df
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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