Cyclohexene → HCID 136358468, compound

HRID 1295020Notes

Reaction equation

HRID 1295020 reaction equation
[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH:12]([CH3:14])[CH3:13])[N:8]=[C:7]2[C:15]1[CH:20]=[CH:19][C:18]([O:21]C)=[CH:17][C:16]=1[CH3:23].B(Br)(Br)Br.C1CCCCC=1>>[F:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH:12]([CH3:14])[CH3:13])[N:8]=[C:7]2[C:15]1[CH:20]=[CH:19][C:18]([OH:21])=[CH:17][C:16]=1[CH3:23]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68885992HCID 68885992, compound

Product 1

HCID 136358468HCID 136358468, compoundYield 96.1%

Procedure

Prepared according to Method D step C from 7-fluoro-1-isobutyl-3-(4-methoxy-2-methyl-phenyl)-1H-indazole (0.364 g, 1.2 mmol), boron tribromide (0.450 mL, 4.6 mmol) and 1.0 mL of cyclohexene to give the product (0.344 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-d2b0547fbb394013a046b9fef2c2f66a
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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