HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → 2-allyl-3-(2,4-dimethoxyphenyl)-7-fluoro-2H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 3-(2,4-dimethoxyphenyl)-7-fluoro-1H-indazole | HCID 178489145 | — |
| Product | 2-allyl-3-(2,4-dimethoxyphenyl)-7-fluoro-2H-indazole | HCID 68882446 | 19.5% |
Reaction Steps
Prepared according to Method D step B from 3-(2,4-dimethoxyphenyl)-7-fluoro-1H-indazole (0.300 g, 1.10 mmol), sodium hydride (60% in oil, 0.058 g, 1.50 mmol) and allyl bromide (0.173 mL, 2.00 mmol) to give the title compound (0.067 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-d352ece94dac4060bdb9ddf5a8abf544 |
| Source note | uspto-grants-2007_07 |