Cyclohexene → HCID 136358470, compound

HRID 1295024Notes

Reaction equation

HRID 1295024 reaction equation
[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[F:13])[C:6]([C:14]2[CH:19]=[CH:18][C:17]([O:20]C)=[CH:16][C:15]=2[O:22]C)=[N:5]1)[CH:2]=[CH2:3].B(Br)(Br)Br.C1CCCCC=1>>[CH2:1]([N:4]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][C:11]=2[F:13])[C:6]([C:14]2[CH:19]=[CH:18][C:17]([OH:20])=[CH:16][C:15]=2[OH:22])=[N:5]1)[CH:2]=[CH2:3]

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68883394HCID 68883394, compound

Product 1

HCID 136358470HCID 136358470, compoundYield 92%

Procedure

Prepared according to Method D step C from 1-allyl-3-(2,4-dimethoxyphenyl)-7-fluoro-1H-indazole (0.187 g, 0.6 mmol), boron tribromide (0.362 mL, 3.80 mmol) and 1.0 mL of cyclohexene to give the product (0.157 g) as a white solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-cf484a10255c42a98e9322af803cf2f6
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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