HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropyl iodide → 2-isopropyl 3-(4-methoxyphenyl)-7-trifluoromethyl-2H-indazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropyl iodide | HCID 6362 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | HCID 178489134 | HCID 178489134 | — |
| Product | 2-isopropyl 3-(4-methoxyphenyl)-7-trifluoromethyl-2H-indazole | HCID 68884186 | 23.8% |
Reaction Steps
Prepared according to Method D step B from 3-(4-methoxyphenyl)-7-trifluoromethyl-1H-indazole (1.0 g, 3.4 mmol), sodium hydride (60% in oil, 0.136 g, 3.4 mmol) and 2-iodopropane (0.34 mL, 3.4 mmol) to give the title compound (0.27 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-50cc5188b5ae417fa669dcfa6a92c594 |
| Source note | uspto-grants-2007_07 |