Cyclohexene → HCID 136358472, compound

HRID 1295029Notes

Reaction equation

HRID 1295029 reaction equation
C[O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[CH:11][CH:12]=[C:13]3[C:17]=2[N:16]([CH2:18][CH2:19][CH3:20])[N:15]=[C:14]3[C:21]2[CH:26]=[CH:25][C:24]([O:27]C)=[CH:23][CH:22]=2)=[CH:5][CH:4]=1.B(Br)(Br)Br.C1CCCCC=1>>[OH:27][C:24]1[CH:23]=[CH:22][C:21]([C:14]2[C:13]3[C:17](=[C:9]([C:6]4[CH:7]=[CH:8][C:3]([OH:2])=[CH:4][CH:5]=4)[CH:10]=[CH:11][CH:12]=3)[N:16]([CH2:18][CH2:19][CH3:20])[N:15]=2)=[CH:26][CH:25]=1

Participants

4

Reactant 3

HCID 8079CyclohexeneHCID 25134Boron tribromideHCID 68882772HCID 68882772, compound

Product 1

HCID 136358472HCID 136358472, compoundYield 76.5%

Procedure

Prepared according to Method D step C from 7-(4-methoxyphenyl)-3-(4-methoxy-phenyl)-1-propyl-1H-indazole (0.04 g, 0.11 mmol), boron tribromide (0.04 mL, 0.43 mmol) and 0.1 mL of cyclohexene to give the product (0.029 g) as an light yellow solid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-5eca09f5a42f4989887e01dde692ac3b
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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