Boron tribromide → HCID 136358475, compound

HRID 1295036Notes

Reaction equation

HRID 1295036 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:10]=1[N:9]([CH2:11][CH2:12][CH3:13])[N:8]=[C:7]2[C:14]1[CH:19]=[CH:18][C:17]([O:20]C)=[C:16]([Cl:22])[CH:15]=1.B(Br)(Br)Br>>[Cl:22][C:16]1[CH:15]=[C:14]([C:7]2[C:6]3[C:10](=[C:2]([Cl:1])[CH:3]=[CH:4][CH:5]=3)[N:9]([CH2:11][CH2:12][CH3:13])[N:8]=2)[CH:19]=[CH:18][C:17]=1[OH:20]

Participants

3

Reactant 2

HCID 25134Boron tribromideHCID 68884157HCID 68884157, compound

Product 1

HCID 136358475HCID 136358475, compoundYield 64%

Procedure

Prepared according to Method D step C from 7-Chloro-3-(3-chloro-4-methoxyphenyl)-1-propyl-1H-indazole (0.39 g, 1.18mmol), BBr3 (0.11 mL, 1.17 mmol) to give the title compound as a white solid (0.24 g, 0.75 mmol, 64%).

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-e9562226c5db4b98b086a7daf6dc70c9
Source dataset
uspto-grants-2007_07
Patent number
US07241791B2

Reaction notes

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