HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,3-Dimethylbutanoyl chloride → 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenyl 3,3-dimethylbutanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,3-Dimethylbutanoyl chloride | HCID 81514 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenol | HCID 135524867 | — |
| Product | 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenyl 3,3-dimethylbutanoate | HCID 68882903 | 88% |
Reaction Steps
Prepared according to Method E from 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenol (0.30 g, 1.0 mmol), 3,3-dimethylbutanoyl chloride (0.167 mL, 1.2 mmol) and N,N-diisopropylethylamine (0.21 mL, 1.2 mmol) to give 0.347 g of the title compound as a white solid, mp 74–75° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-2288f41d8d0449e9968b2b4aac7e5425 |
| Source note | uspto-grants-2007_07 |