HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propionyl chloride → 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenyl propionate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propionyl chloride | HCID 62324 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenol | HCID 135524867 | — |
| Product | 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenyl propionate | HCID 68884410 | — |
Reaction Steps
Prepared according to Method E from 4-(1-cyclopentyl-7-fluoro-1H-indazol-3-yl)phenol (0.30 g, 1.0 mmol), propanoyl chloride (0.105 mL, 1.2 mmol) and N,N-diisopropylethylamine (0.21 mL, 1.2 mmol) to give 0.284 g to the title compound as a white solid, mp 60–61° C.;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241791B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-a793d86a0934471b83851a290345130c |
| Source note | uspto-grants-2007_07 |