Sodium Hydroxide → HCID 58907034, compound

Participants

Reaction Steps

To a solution of example 1 (300 mg, 0.5 mmol) in EtOH was added a 1N NaOH solution and the mixture was stirred to reflux for 1 hour and then the solvant was evaporated off. The residue was acidified with a 1N HCl solution and the precipitate was purified by flash chromatography using DCW/MeOH (90/10), to give the title compound (75 mg, 0.13 mmol) as crystals.

Provenance & Evidence