Iodoethane → HCID 58906998, compound

Participants

Reaction Conditions

Reaction Steps

A solution of example 15 (1.8 g, 4 mmol) in MIK (50 mL) was treated with Cs2CO3 (5 g, excess) and Ethyl iodide (2 mL). The resulting mixture was stirred at 95° C. overnight under pressure. After cooling to rt the reaction mixture was filtered off and the filtrate was evaporated off. The residue was diluted with DCM, washed with water and drying over Na2SO4 and filtration evaporation to give the title compound (320 mg, 0.68 mmol) as oil in a 17% yield after purification by flash chromatography.

Provenance & Evidence