HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-[2-(1H-indol-5-yloxy)-ethyl]-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester → HCID 66821322, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-[2-(1H-indol-5-yloxy)-ethyl]-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester | HCID 66821083 | — |
| Reactant | (5-Methanesulfonyl-pyridin-3-yl)-propynoic acid ethyl ester | HCID 67427397 | — |
| Product | HCID 66821322 | HCID 66821322 | 80% |
Reaction Steps
The title compound was synthesized from (5-methanesulfonyl-pyridin-3-yl)-propynoic acid ethyl ester and 7-[2-(1H-indol-5-yloxy)-ethyl]-3,4-dihydro-2H-[1,8]naphthyridine-1-carboxylic acid tert-butyl ester using the procedure described in Example 16, step (d1), in 80% yield. Mass Spectrum (LCMS, ESI) calculated for C29H31N4O5S: 547.2 (M-Boc+H); found 547.3 (−Boc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07241789B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-eda7547555d8490ebd190662a93afdde |
| Source note | uspto-grants-2007_07 |