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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1295176Generated: October 31, 2026

2-[6-(Methylamino)-2-pyridyl]ethan-1-ol → 3-[5-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-indol-1-yl}-hexanoic acid ethyl ester

https://huagongshe.com/reaction/1295176

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[6-(Methylamino)-2-pyridyl]ethan-1-olHCID 10534858—
Reactant3-(5-Hydroxy-indol-1-yl)-hexanoic acid ethyl esterHCID 67426394—
Product3-[5-[2-(6-Methylamino-pyridin-2-yl)-ethoxy]-indol-1-yl}-hexanoic acid ethyl esterHCID 6742771825%

Reaction Steps

The title compound was synthesized from 2-(6-methylamino-pyridin-2-yl)-ethanol and 3-(5-hydroxy-indol-1-yl)-hexanoic acid ethyl ester using the procedure described in Example 14, step (c), in 25% yield. The crude product was used in the next step without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241789B2
Source datasetuspto-grants-2007_07
ORD IDord-e931377ee4a24c7baca32a9b944e7f94
Source noteuspto-grants-2007_07