Ethanol → 3-Bromo-5-ethoxypyridine

HRID 1295190Notes

Reaction equation

HRID 1295190 reaction equation
Br[C:2]1[CH:3]=[N:4][CH:5]=[C:6]([Br:8])[CH:7]=1.[CH2:9]([OH:11])[CH3:10]>>[Br:8][C:6]1[CH:5]=[N:4][CH:3]=[C:2]([O:11][CH2:9][CH3:10])[CH:7]=1

Participants

3

Reactant 2

HCID 702EthanolHCID 693693,5-Dibromopyridine

Product 1

HCID 122934803-Bromo-5-ethoxypyridineYield 60%

Procedure

The title compound was synthesized from 3,5-dibromopyridine and ethanol using the procedure described in Example 53, step (a) in 60% yield. 1H NMR (CDCl3) δ 8.27 (bs, 1H), 8.23 (bs, 1H), 7.33 (m, 1H), 4.06 (q, 2H, J=7.0 Hz), 1.43 (t, 3H, J=7.0 Hz).

Sources & evidence

ORD record
ord-a6b03b7b5cc746cda1740cad9db0fc7b
Source dataset
uspto-grants-2007_07
Patent number
US07241789B2

Reaction notes

Loading…