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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1295405Generated: October 26, 2026

Ethylamine → 2-Chloro-N-ethyl-5-hydroxybenzamide

https://huagongshe.com/reaction/1295405

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthylamineHCID 6341—
Reactant2-Chloro-5-hydroxybenzoic acidHCID 458210—
Product2-Chloro-N-ethyl-5-hydroxybenzamideHCID 58907486—

Reaction Steps

The title compound was prepared from 2-chloro-5-hydroxybenzoic acid and ethylamine, using a method similar to that used for preparation 52, as a colourless solid. 1HNMR (400 MHz, CDCl3) δ: 1.22 (3H, t), 3.42–3.49 (2H, m), 6.48–6.52 (1H, m), 6.80 (1H, dd), 7.13 (1H, d), 7.38 (1H, d); LRMS ESI m/z 200 [M+H]+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07241810B2
Source datasetuspto-grants-2007_07
ORD IDord-1887cb4f412d407db3003ab77cc1f53a
Source noteuspto-grants-2007_07