Nitric Acid → HCID 11097269, compound

HRID 1295576Notes

Reaction equation

HRID 1295576 reaction equation
[C:1]([O:9][C:10]1[CH:15]=[CH:14][C:13]([OH:16])=[CH:12][CH:11]=1)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N+:17]([O-])([OH:19])=[O:18]>C(O)(=O)C>[C:1]([O:9][C:10]1[CH:11]=[CH:12][C:13]([OH:16])=[C:14]([N+:17]([O-:19])=[O:18])[CH:15]=1)(=[O:8])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

4

Reactant 2

HCID 944Nitric AcidHCID 75549p-Hydroxyphenyl benzoate

Product 1

HCID 11097269HCID 11097269, compoundYield 97%

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Conditions

Temperature
20 °C

Procedure

To a stirred solution of 4-hydroxyphenyl benzoate (10 g, 47 mmol) in acetic acid (250 mL) was added, dropwise with external ice-bath cooling, nitric acid (d=1.42, 2.9 mL) (T=10° C.). The mixture was warmed to 20° C. and stirred for a further 56 h. The solution was evaporated in vacuo and water added to the residue. The resulting yellow solid was collected by filtration, washed with water and dried in vacuo to give the title compound (11.8 g, 97%).

Workup

  1. temperaturecooling
  2. customThe solution was evaporated in vacuo and water
  3. additionadded to the residue
  4. filtrationThe resulting yellow solid was collected by filtration
  5. washwashed with water
  6. customdried in vacuo

Sources & evidence

ORD record
ord-d256f16365a24fdea459d23620e4e7b7
Source dataset
uspto-grants-2007_07
Patent number
US07244726B2

Reaction notes

Loading…