5-(2-Bromoethoxy)-2-methylquinoline → 6-{-[2-(2-Methylquinolin-5-oxy)ethyl]piperidin-4-ylidenemethyl}-1,3-dihydroindol-2-one

HRID 1295593Notes

Reaction equation

HRID 1295593 reaction equation
[NH:1]1[CH2:6][CH2:5][C:4](=[CH:7][C:8]2[CH:16]=[C:15]3[C:11]([CH2:12][C:13](=[O:17])[NH:14]3)=[CH:10][CH:9]=2)[CH2:3][CH2:2]1.Br[CH2:19][CH2:20][O:21][C:22]1[CH:31]=[CH:30][CH:29]=[C:28]2[C:23]=1[CH:24]=[CH:25][C:26]([CH3:32])=[N:27]2>>[CH3:32][C:26]1[CH:25]=[CH:24][C:23]2[C:22]([O:21][CH2:20][CH2:19][C:7](=[C:4]3[CH2:5][CH2:6][NH:1][CH2:2][CH2:3]3)[C:8]3[CH:16]=[C:15]4[C:11]([CH2:12][C:13](=[O:17])[NH:14]4)=[CH:10][CH:9]=3)=[CH:31][CH:30]=[CH:29][C:28]=2[N:27]=1

Participants

3

Reactant 2

HCID 117371925-(2-Bromoethoxy)-2-methylquinolineHCID 179651476-(Piperidin-4-ylidenemethyl)-1,3-dihydroindol-2-one

Product 1

HCID 694204996-{-[2-(2-Methylquinolin-5-oxy)ethyl]piperidin-4-ylidenemethyl}-1,3-dihydroindol-2-one

Procedure

The title compound was prepared from 6-(piperidin-4-ylidenemethyl)-1,3-dihydroindol-2-one and 5-(2-bromoethoxy)-2-methylquinoline using a similar method to that of Description 11.

Sources & evidence

ORD record
ord-32e528c28edd442192e66c5dba8effa5
Source dataset
uspto-grants-2007_07
Patent number
US07244726B2

Reaction notes

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