HRID129567

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10376290

未命名化合物

结构：CC(C)(c1ccccc1)n1nnc(-c2ccccc2-c2ccc(C=O)cc2)n1

HCID15225578

未命名化合物

PRODUCTS

生成物

结构：CCCCn1c(C(O)c2ccc(-c3ccccc3-c3nnn(C(C)(C)c4ccccc4)n3)cc2)c(C(=O)O)c2ccccc21

HCID19371907

未命名化合物

PROCEDURE

实验过程

reacting the 2-lithiated 1-butyl-1H-indole-3-carboxylic acid with protected 2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-carbaldehyde to give 1-butyl-2-{2'-[2-(1-methyl-1-phenylethyl)-2H-tetrazol-5-yl]biphenyl-4-yl(hydroxy)methyl}-1H-indole-3-carboxylic acid;

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5b3d92077a6c42138fb91edf73932c78
来源数据集: uspto-grants-1995_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05468867
来源说明: uspto-grants-1995_11

反应 SMILES

[CH2:1]([N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7]([C:14]([OH:16])=[O:15])=[CH:6]1)[CH2:2][CH2:3][CH3:4].[CH3:17][C:18]([N:26]1[N:30]=[N:29][C:28]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][C:32]=2[C:37]2[CH:42]=[CH:41][C:40]([CH:43]=[O:44])=[CH:39][CH:38]=2)=[N:27]1)([C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=1)[CH3:19]>>[CH2:1]([N:5]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7]([C:14]([OH:16])=[O:15])=[C:6]1[CH:43]([C:40]1[CH:39]=[CH:38][C:37]([C:32]2[CH:33]=[CH:34][CH:35]=[CH:36][C:31]=2[C:28]2[N:29]=[N:30][N:26]([C:18]([CH3:19])([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[CH3:17])[N:27]=2)=[CH:42][CH:41]=1)[OH:44])[CH2:2][CH2:3][CH3:4]