Cycloheptanecarbonyl chloride → HCID 21843741, compound
Reaction equation
[NH2:1][CH2:2][CH:3]1[CH2:12][CH2:11][C:10]2[C:5](=[C:6]([O:13][CH3:14])[CH:7]=[CH:8][CH:9]=2)[O:4]1.[CH:15]1([C:22](Cl)=[O:23])[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1>>[CH3:14][O:13][C:6]1[CH:7]=[CH:8][CH:9]=[C:10]2[C:5]=1[O:4][CH:3]([CH2:2][NH:1][C:22]([CH:15]1[CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16]1)=[O:23])[CH2:12][CH2:11]2Participants
3
Procedure
The title compound is prepared analogously to the instructions of Example XII from 2-aminomethyl-8-methoxychroman and cycloheptanecarbonyl chloride, and is further reacted directly.
Workup
- customis further reacted directly
Sources & evidence
- ORD record
- ord-bfcbaa9176774da48bf54ff55b791db6
- Source dataset
- uspto-grants-1995_11
- Patent number
- US05468882
Reaction notes
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