HCID 58910028, compound → HCID 22929848, compound

Participants

Reaction Steps

After dissolving tert-butyl N-[4-(bromomethyl)-5-cyano-2-ethoxybenzoyl]-N-methylcarbamate (39.9 g) in dichloromethane (300 ml), trifluoroacetic acid (50 ml) was added and the mixture was stirred at room temperature for 30 minutes. The reaction mixture was concentrated and the residue was purified by silica gel column chromatography (solvent: n-hexane-ethyl acetate) to yield the title compound (19.77 g) as a white solid.

Provenance & Evidence