HCID 22929892, compound → HCID 178485230, compound

Participants

Reaction Steps

After dissolving N1-methyl-4-(azidomethyl)-5-cyano-2-(dimethylamino)benzamide (755 mg, 2.9 mmol) in methanol (50 ml), 10% palladium-carbon (50% wet) (0.2 g) was added prior to catalytic reduction for 30 minutes at room temperature and normal pressure. The catalyst was separated off, the solvent was distilled off under reduced pressure and ethyl acetate was added to the residue for crystallization. This was filtered off to yield the title compound (283 mg) as a faint yellow powder. (42% yield)

Provenance & Evidence