Tetra-n-butylammonium tribromide → HCID 22929748, compound

Participants

Reaction Steps

Tetra-n-butylammonium tribromide (321 mg, 0.666 mmol) was added to a solution of the 1-[3-(tert-butyl)-5-ethoxy-4-hydroxyphenyl]-1-ethanone (150 mg, 0.635 mmol) in methylene chloride-methanol (4 ml:1 ml) and the mixture was stirred at room temperature for 8 hours. After distilling off the solvent under reduced pressure, the residue was purified by silica gel column chromatography (solvent: n-hexane-ethyl acetate) to yield the title compound (60 mg) as colorless crystals.

Provenance & Evidence