Acetaldehyde → HCID 22504734, compound

HRID 1296057Notes

Reaction equation

HRID 1296057 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[CH:10][C:11]([NH2:14])=[N:12][CH:13]=2)=[CH:4][CH:3]=1.[CH:15](=O)[CH3:16]>>[CH2:15]([NH:14][C:11]1[CH:10]=[CH:9][C:8]([C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)=[CH:13][N:12]=1)[CH3:16]

Participants

3

Reactant 2

HCID 177AcetaldehydeHCID 225048025-(4-Fluorophenyl)pyridin-2-amine

Product 1

HCID 22504734HCID 22504734, compound

Procedure

Compound 70A was reacted with acetaldehyde in a manner analogous to Compound 63C to give the title product. 400 MHz 1H NMR (DMSO-d6) δ ppm 1.1 (t, 3H) 3.2 (q, 2H) 6.6 (m, 2H) 7.2 (m, 2H) 7.5 (m, 3H) 8.2 (d, J=2.0 Hz, 1H).

Sources & evidence

ORD record
ord-97007e7bc64c4535b9c80c652a9f3c99
Source dataset
uspto-grants-2007_07
Patent number
US07244763B2

Reaction notes

Loading…