2-(4-Fluoro-phenyl)-benzooxazole-5-carboxylic acid methyl ester → [2-(4-Fluoro-phenyl)-benzooxazol-5-yl]-methanol

HRID 1296064Notes

Reaction equation

HRID 1296064 reaction equation
C[O:2][C:3]([C:5]1[CH:6]=[CH:7][C:8]2[O:12][C:11]([C:13]3[CH:18]=[CH:17][C:16]([F:19])=[CH:15][CH:14]=3)=[N:10][C:9]=2[CH:20]=1)=O.FC1C=C(C2OC3C=CC(CO)=CC=3N=2)C=CC=1>>[F:19][C:16]1[CH:15]=[CH:14][C:13]([C:11]2[O:12][C:8]3[CH:7]=[CH:6][C:5]([CH2:3][OH:2])=[CH:20][C:9]=3[N:10]=2)=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 207708272-(4-Fluoro-phenyl)-benzooxazole-5-carboxylic acid methyl esterHCID 22504740HCID 22504740, compound

Product 1

HCID 22504876[2-(4-Fluoro-phenyl)-benzooxazol-5-yl]-methanol

Procedure

Compound 74A was reacted in a manner analogous to Compound 69B to give the title product. MS m/z 244 (M+1).

Sources & evidence

ORD record
ord-9d4dcfc1bbe944d987ad0e7df5dd5fa2
Source dataset
uspto-grants-2007_07
Patent number
US07244763B2

Reaction notes

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