HCID 22504861, compound → HCID 22504854, compound

HRID 1296065Notes

Reaction equation

HRID 1296065 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:16]=[CH:15][C:14]([CH2:17]O)=[CH:13][C:11]=3[N:12]=2)=[CH:4][CH:3]=1.[Cl:19]CC1C=CC2OC(C3C=CC=C(F)C=3)=NC=2C=1>>[Cl:19][CH2:17][C:14]1[CH:15]=[CH:16][C:10]2[O:9][C:8]([C:5]3[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=3)=[N:12][C:11]=2[CH:13]=1

Participants

3

Reactant 2

HCID 22504861HCID 22504861, compoundHCID 22504876[2-(4-Fluoro-phenyl)-benzooxazol-5-yl]-methanol

Product 1

HCID 22504854HCID 22504854, compound

Procedure

Compound 74B was reacted in a manner analogous to Compound 69C to give the title product. 400 MHz 1H NMR (DMSO-d6) δ □ ppm 4.9 (s, 2H) 7.4 (t, J=9.0 Hz, 2H) 7.5 (dd, J=8.4, 1.8 Hz, 1H) 7.7 (d, J=9.0 Hz, 1H) 7.8 (d, J=1.2 Hz, 1H) 8.2 (dd, J=9.0, 5.4 Hz, 2H).

Sources & evidence

ORD record
ord-2641e03ca4b44883890452e58c9d8599
Source dataset
uspto-grants-2007_07
Patent number
US07244763B2

Reaction notes

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