Methyl 2-(6-hydroxy-1-benzofuran-3-yl)acetate → HCID 22504842, compound

HRID 1296074Notes

Reaction equation

HRID 1296074 reaction equation
C[O:2][C:3](=[O:15])[CH2:4][C:5]1[C:9]2[CH:10]=[CH:11][C:12]([OH:14])=[CH:13][C:8]=2[O:7][CH:6]=1.[F:16][C:17]([F:35])([F:34])[C:18]1[CH:33]=[CH:32][C:21]([CH2:22][O:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[CH2:30]Cl)=[CH:20][CH:19]=1>>[F:16][C:17]([F:34])([F:35])[C:18]1[CH:33]=[CH:32][C:21]([CH2:22][O:23][C:24]2[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=2[CH2:30][O:14][C:12]2[CH:11]=[CH:10][C:9]3[C:5]([CH2:4][C:3]([OH:2])=[O:15])=[CH:6][O:7][C:8]=3[CH:13]=2)=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 20770861Methyl 2-(6-hydroxy-1-benzofuran-3-yl)acetateHCID 22280194HCID 22280194, compound

Product 1

HCID 22504842HCID 22504842, compound

Procedure

The title compound was prepared in the manner analogous to step 1 of Example 80 using (6-hydroxy-benzofuran-3-yl)-acetic acid methyl ester and 1-(4-trifluoromethyl-benzyloxy)-2-chloromethyl-benzene. MS m/z 471 (M+1).

Sources & evidence

ORD record
ord-366300c495e04da38ae91d6aa94ffc85
Source dataset
uspto-grants-2007_07
Patent number
US07244763B2

Reaction notes

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