HCID 22494136, compound → HCID 22494177, compound

Participants

Reaction Steps

29 mg of 3-(7-[(t-butoxycarbonyl)amino]methylbenzo[b]furan-5-yl)-2-isopropoxypropionic acid ethyl ester was dissolved in ethanol, and 30 mg of 10% palladium carbon was added, followed by stirring for 3 days at room temperature in hydrogen atmosphere. The reaction mixture was filtered through Celite, and the filtrate was concentrated, to give 27 mg of 3-(7-[(t-butoxycarbonyl)amino]methyl-2,3-dihydrobenzo[b]furan-5-yl)-2-isopropoxypropionic acid ethyl ester was obtained.

Provenance & Evidence