Hydrogen Bromide → 4-(4-aminobutyl)phenol Hydrobromide

Participants

Role	Name	HCID	Charge
Reactant	Hydrogen Bromide	HCID 260	—
Reactant	4-(4-Methoxyphenyl)butan-1-amine	HCID 10583506	—
Product	4-(4-aminobutyl)phenol Hydrobromide	HCID 11550522	90%

Reaction Steps

Amine III (2.32 g, 0.012 mol) was stirred in boiling 48% HBr (50 mL) for 3 h. After the reaction was completed, argon was bubbled through the solution and the solvent was evaporated under reduced pressure. The solid residue was dried above KOH to provide 3.1 g (90%) of IV. API MS m/z=166[C10H15NO+H]+

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07247636B2
Source dataset	uspto-grants-2007_07
ORD ID	ord-ab581f4621fa495bbd7aafd0b0446a8d
Source note	uspto-grants-2007_07