HCID 60108780, compound → HCID 60108785, compound

Participants

Reaction Steps

A mixture of 4-(1H-indol-7-yl)-3,6-dihydro-2H-pyridine-1-carboxylic acid tert-butyl ester XVII (700 mg, 2.3 mmol) and 10% Pd/C (70 mg) in ethanol (75 mL) was placed under H2 atmosphere on the parr shaker at 50 psi, and was shaken overnight. The reaction mixture was filtered through a plug of celite capped with a glass filter. The filtrate was concentrated to afford (680 mg, 95%) of 4-(1H-indol-7-yl)-piperidine-1-carboxylic acid tert-butyl ester XVIII.

Provenance & Evidence