Pyripropanol → HCID 18186889, compound

HRID 1296663Notes

Reaction equation

HRID 1296663 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH2:7][CH2:8][CH2:9][OH:10].[Cl:11][C:12]1[CH:17]=[N:16][CH:15]=[C:14](Cl)[N:13]=1>>[Cl:11][C:12]1[CH:17]=[N:16][CH:15]=[C:14]([O:10][CH2:9][CH2:8][CH2:7][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[N:13]=1

Participants

3

Reactant 2

HCID 72922PyripropanolHCID 785042,6-Dichloropyrazine

Product 1

HCID 18186889HCID 18186889, compound

Procedure

The title compound was prepared according to the procedure of example 50, step 1, starting from 2-pyridinepropanol (4.08 g, 29.7 mmol), K-t-BuO (3.17 g, 28.3 mmol) and 2,6-dichloropyrazine (3.69 g, 24.8 mmol). The yield of the title compound was 5.18 g (84%) and was obtained as an oil. Anal. (C12H12ClN3O) C, H, N.

Workup

  1. customThe title compound was prepared
  2. customwas obtained as an oil

Sources & evidence

ORD record
ord-d19cc571cfa14d32819bcb2d037fc292
Source dataset
uspto-grants-2007_07
Patent number
US07247633B2

Reaction notes

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