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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1296767Generated: October 30, 2026

3,4-Dimethylbenzoic acid → 2-(5-Carbamimidoyl-2-((3,4-dimethylbenzamido)methyl)phenylamino)acetic acid

https://huagongshe.com/reaction/1296767

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3,4-Dimethylbenzoic acidHCID 12073—
ReactantBenzyl 2-(2-(aminomethyl)-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino)acetate hydrochlorideHCID 69490392—
Product2-(5-Carbamimidoyl-2-((3,4-dimethylbenzamido)methyl)phenylamino)acetic acidHCID 11739710—

Reaction Steps

Compound 58d was reacted with 3,4-dimethylbenzoic acid and subsequently hydrogenated according to the the procedure described in Example 58, to give Example 61. ESI-MS m/e 355.5 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07247654B2
Source datasetuspto-grants-2007_07
ORD IDord-0068e8abfa60466a91ea5c38000352ae
Source noteuspto-grants-2007_07