反应详情

To a solution of compound 65d (0.170 g, 0.37 mmol) in ethanol (3 mL) was added 10% palladium/carbon (30 mg). The reaction mixture was hydrogenated (1 atm) overnight. The solution was filtered and the filtrate was concentrated to give compound 65e (0.159 g, 100%) as a brown oily solid. ESI-MS m/e 430.5 (M+1).

1. custom(1 atm) overnight
2. filtrationThe solution was filtered
3. concentrationthe filtrate was concentrated