3-Hydroxybenzoic Acid → HCID 11267863, compound

HRID 1296776Notes

Reaction equation

HRID 1296776 reaction equation
Cl.[NH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:14]=C(C)O[N:11]=2)=[CH:6][C:5]=1[NH:16][CH2:17][C:18]([O:20]CC1C=CC=CC=1)=[O:19].[OH:28][C:29]1[CH:30]=[C:31]([CH:35]=[CH:36][CH:37]=1)[C:32](O)=[O:33]>>[C:10]([C:7]1[CH:8]=[CH:9][C:4]([CH2:3][NH:2][C:32](=[O:33])[C:31]2[CH:35]=[CH:36][CH:37]=[C:29]([OH:28])[CH:30]=2)=[C:5]([NH:16][CH2:17][C:18]([OH:20])=[O:19])[CH:6]=1)(=[NH:11])[NH2:14]

Participants

3

Reactant 2

HCID 74203-Hydroxybenzoic AcidHCID 69490392Benzyl 2-(2-(aminomethyl)-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino)acetate hydrochloride

Product 1

HCID 11267863HCID 11267863, compound

Procedure

Compound 58d was reacted with 3-hydroxybenzoic acid and subsequently hydrogenated according to the procedure described in Example 58, to give example 67. ESI-MS m/e 343.5 (M+1).

Workup

  1. customto give example 67

Sources & evidence

ORD record
ord-01accb74a40842729d2daa12d9baa79b
Source dataset
uspto-grants-2007_07
Patent number
US07247654B2

Reaction notes

Loading…