4-Methyl-m-anisic acid → HCID 11462838, compound

HRID 1296777Notes

Reaction equation

HRID 1296777 reaction equation
Cl.[NH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([C:10]2[N:14]=C(C)O[N:11]=2)=[CH:6][C:5]=1[NH:16][CH2:17][C:18]([O:20]CC1C=CC=CC=1)=[O:19].[CH3:28][O:29][C:30]1[CH:31]=[C:32]([CH:36]=[CH:37][C:38]=1[CH3:39])[C:33](O)=[O:34]>>[C:10]([C:7]1[CH:8]=[CH:9][C:4]([CH2:3][NH:2][C:33](=[O:34])[C:32]2[CH:36]=[CH:37][C:38]([CH3:39])=[C:30]([O:29][CH3:28])[CH:31]=2)=[C:5]([NH:16][CH2:17][C:18]([OH:20])=[O:19])[CH:6]=1)(=[NH:11])[NH2:14]

Participants

3

Reactant 2

HCID 815794-Methyl-m-anisic acidHCID 69490392Benzyl 2-(2-(aminomethyl)-5-(5-methyl-1,2,4-oxadiazol-3-yl)phenylamino)acetate hydrochloride

Product 1

HCID 11462838HCID 11462838, compound

Procedure

Compound 58d was reacted with 3-methoxy-4-methylbenzoic acid and subsequently hydrogenated according to the procedure described in Example 58, to give example 68. ESI-MS m/e 371.5 (M+1).

Workup

  1. customto give example 68

Sources & evidence

ORD record
ord-20270f3e300e459e891b2b69ca8a1d76
Source dataset
uspto-grants-2007_07
Patent number
US07247654B2

Reaction notes

Loading…