HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178418361, compound → HCID 178483181, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Reactant | HCID 178483180 | HCID 178483180 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 178483181 | HCID 178483181 | — |
Reaction Steps
To a solution 0.2 g (0.42 mmoles) of N-methyl-N-phenethyl-2-[5-benzyloxy-3-(2-tetrazol-5-ylvinyl)indol-1-yl]acetamide in 30 ml of ethanol is added 0.08 g of 10% palladium on carbon and the mixture is shaken under 30 psi of hydrogen for 4 hours. The mixture is filtered and the filtrate concentrated in vacuo. The residue is crystallized from methylene chloride to give N-methyl-N-phenethyl-2-[5-benzyloxy-3-(2-tetrazol-5-yl)ethylindol-1-yl]acetamide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05468898 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-e7076db49a6e4ed4a0365d8340a2f03f |
| Source note | uspto-grants-1995_11 |