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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 129685Generated: October 29, 2026

HCID 178418361, compound → HCID 178483181, compound

https://huagongshe.com/reaction/129685

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 178418361HCID 178418361—
ReactantHCID 178483180HCID 178483180—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
ProductHCID 178483181HCID 178483181—

Reaction Steps

To a solution 0.2 g (0.42 mmoles) of N-methyl-N-phenethyl-2-[5-benzyloxy-3-(2-tetrazol-5-ylvinyl)indol-1-yl]acetamide in 30 ml of ethanol is added 0.08 g of 10% palladium on carbon and the mixture is shaken under 30 psi of hydrogen for 4 hours. The mixture is filtered and the filtrate concentrated in vacuo. The residue is crystallized from methylene chloride to give N-methyl-N-phenethyl-2-[5-benzyloxy-3-(2-tetrazol-5-yl)ethylindol-1-yl]acetamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05468898
Source datasetuspto-grants-1995_11
ORD IDord-e7076db49a6e4ed4a0365d8340a2f03f
Source noteuspto-grants-1995_11