4-Chlororesorcinol → HCID 58913524, compound

Participants

Reaction Steps

This compounds was synthesised in the same manner as described above. [4-(3-Cyano-propoxy)-phenyl]-acetic acid (0.5 g, 2.28 mmol), 4-chlororesorcinol (0.33 g, 2.28 mmol), boron trifloride etherate (5 ml). After standing for two hours a precipitate formed which was filtered, washed (water), and dried to give 4-{4-[2-(5-Chloro-2,4-dihydroxy-phenyl)-2-oxo-ethyl]-phenoxy}butyronitrile as a white solid (0.62 g, 78.7%); Rf 0.6 hexane/ethyl acetate (20/80).

Provenance & Evidence