Phenylacetic Acid → 6-Chloro-7-hydroxy-3-phenyl-chromen-4-one

関与物質

反応手順

This compounds was synthesised in the same manner as described above. Chlororesorcinol (0.87 g, 6 mmol), phenylacetic acid (0.82 g, 6 mmol), BF3Et2O (4 ml), PCl5 (1.9 g, 9.1 mmol), DMF (5 ml and 10 ml). The pink precipitate formed was filtered and re-crystallized from methanol to give 6-Chloro-7-hydroxy-3-phenyl-chromen-4-one as fine light pink crystals (1.4 g, 85%); Rf 0.6 ethyl acetate/hexane (75/25).

情報源と証拠