4-Chlororesorcinol → HCID 58913538, compound

Participants

Reaction Steps

This compounds was synthesised in the same manner as described above. 4-Chlororesorcinol (2.0 g, 13.8 mmol), 2-bromophenyl acetic acid (2.98 g, 13.8 mmol), BF3Et2O (8 ml), PCl5 (4.3 g, 20.6 mmol), DMF (8 ml and 12 ml). The precipitate formed was filtered and re-crystallized from methanol to give 3-(2-Bromo-phenyl)-6-chloro-7-hydroxy-chromen-4-one as a white solid (1.9 g, 39.1%); Rf 0.85 ethyl acetate/hexane (75/25).

Provenance & Evidence